The Vitalé Protocol

What we recommend,
and why.

GLP-1 therapy creates specific nutritional gaps — protein intake, muscle preservation, and key micronutrients like zinc, magnesium, B12, and D3. We don't manufacture supplements. We curate clinical-grade products from three brands we trust: Thorne, Momentous, and Ritual.

This page is an editorial position, not a product catalog. Every recommendation below is based on clinical evidence and alignment with what GLP-1 users actually need.

By stage

Your needs change as you progress. These are the supplements we recommend at each stage.

Weeks 1–4

Side effect management

Thorne

Magnesium Bisglycinate

Highly bioavailable form that supports GI motility and helps manage the nausea and digestive disruption common in the first month on GLP-1 therapy.

Shop on Thorne

Momentous

Collagen Peptides

Supports gut lining integrity during the early weeks when appetite is suppressed and food intake is limited.

Shop on Momentous

Ritual

Essential Protein

Clean-label daily protein shake for members struggling to hit protein targets when appetite is dramatically reduced.

Shop on Ritual

Thorne

Basic Nutrients 2/Day

Comprehensive multivitamin baseline. GLP-1 users often reduce total food volume significantly — a clinical-grade multi closes the micronutrient gap.

Shop on Thorne

Thorne

Zinc Picolinate

GLP-1 therapy commonly disrupts taste and smell. Zinc supports sensory recovery and immune function.

Shop on Thorne

Thorne

Vitamin B12 (Methylcobalamin)

B12 depletion is common on GLP-1 therapy and contributes to the fatigue members often report in weeks 2-4.

Shop on Thorne

Weeks 5–12

Nutrition optimization

Ritual

Essential Protein

Clean-label daily protein shake for members struggling to hit protein targets when appetite is dramatically reduced.

Shop on Ritual

Thorne

Basic Nutrients 2/Day

Comprehensive multivitamin baseline. GLP-1 users often reduce total food volume significantly — a clinical-grade multi closes the micronutrient gap.

Shop on Thorne

Thorne

Vitamin B12 (Methylcobalamin)

B12 depletion is common on GLP-1 therapy and contributes to the fatigue members often report in weeks 2-4.

Shop on Thorne

Momentous

Essential Protein

Leucine-forward whey protein isolate engineered for muscle protein synthesis. The highest-quality option for hitting protein targets at 0.7-1g per lb of body weight.

Shop on Momentous

Momentous

Creatine Monohydrate

The most studied supplement in sports science. Supports muscle energy, strength, and lean mass preservation during weight loss.

Shop on Momentous

Thorne

Whey Protein Isolate

NSF Certified for Sport. A clinical-grade protein option for members who prefer Thorne's third-party testing and physician-grade sourcing.

Shop on Thorne

Thorne

Vitamin D3 with K2

Rapid weight loss on GLP-1 increases bone density risk. D3 and K2 work together to support calcium utilization and bone health.

Shop on Thorne

Ritual

Essential for Women 18+

Women-specific multivitamin with forms of iron and folate that address the nutritional gaps women on GLP-1 most commonly face.

Shop on Ritual

Thorne

Iron Bisglycinate

Women reducing red meat intake on GLP-1 often become iron-deficient. This is the gentlest, most absorbable form.

Shop on Thorne

Month 3 and beyond

Muscle preservation & sustainability

Thorne

Basic Nutrients 2/Day

Comprehensive multivitamin baseline. GLP-1 users often reduce total food volume significantly — a clinical-grade multi closes the micronutrient gap.

Shop on Thorne

Momentous

Essential Protein

Leucine-forward whey protein isolate engineered for muscle protein synthesis. The highest-quality option for hitting protein targets at 0.7-1g per lb of body weight.

Shop on Momentous

Momentous

Creatine Monohydrate

The most studied supplement in sports science. Supports muscle energy, strength, and lean mass preservation during weight loss.

Shop on Momentous

Thorne

Whey Protein Isolate

NSF Certified for Sport. A clinical-grade protein option for members who prefer Thorne's third-party testing and physician-grade sourcing.

Shop on Thorne

Thorne

Vitamin D3 with K2

Rapid weight loss on GLP-1 increases bone density risk. D3 and K2 work together to support calcium utilization and bone health.

Shop on Thorne

Ritual

Essential for Women 18+

Women-specific multivitamin with forms of iron and folate that address the nutritional gaps women on GLP-1 most commonly face.

Shop on Ritual

Thorne

Iron Bisglycinate

Women reducing red meat intake on GLP-1 often become iron-deficient. This is the gentlest, most absorbable form.

Shop on Thorne

Momentous

HMB

The single most evidence-backed ingredient for muscle preservation during a caloric deficit. This is the core of the Vitalé muscle protocol.

Shop on Momentous

Momentous

Collagen + Vitamin C

Connective tissue support during significant weight loss. Vitamin C is the cofactor that enables collagen synthesis.

Shop on Momentous

Thorne

Amino Complex

Complete essential amino acid profile for members doing resistance training. Supports recovery and preserves lean mass.

Shop on Thorne

Thorne

Omega-3 with CoQ10

Cardiovascular support that stacks with the cardiac benefits of GLP-1 therapy itself. A long-term foundation supplement.

Shop on Thorne

Ritual

Essential Multivitamin

Clean-label, transparent-sourcing multi for ongoing micronutrient support once members are past the adjustment phase.

Shop on Ritual

By goal

Products organized by what you're solving for.

By goal

Muscle preservation

Ritual

Essential Protein

Clean-label daily protein shake for members struggling to hit protein targets when appetite is dramatically reduced.

Shop on Ritual

Momentous

Essential Protein

Leucine-forward whey protein isolate engineered for muscle protein synthesis. The highest-quality option for hitting protein targets at 0.7-1g per lb of body weight.

Shop on Momentous

Momentous

Creatine Monohydrate

The most studied supplement in sports science. Supports muscle energy, strength, and lean mass preservation during weight loss.

Shop on Momentous

Thorne

Whey Protein Isolate

NSF Certified for Sport. A clinical-grade protein option for members who prefer Thorne's third-party testing and physician-grade sourcing.

Shop on Thorne

Momentous

HMB

The single most evidence-backed ingredient for muscle preservation during a caloric deficit. This is the core of the Vitalé muscle protocol.

Shop on Momentous

Momentous

Collagen + Vitamin C

Connective tissue support during significant weight loss. Vitamin C is the cofactor that enables collagen synthesis.

Shop on Momentous

Thorne

Amino Complex

Complete essential amino acid profile for members doing resistance training. Supports recovery and preserves lean mass.

Shop on Thorne

By goal

Micronutrient replenishment

Thorne

Basic Nutrients 2/Day

Comprehensive multivitamin baseline. GLP-1 users often reduce total food volume significantly — a clinical-grade multi closes the micronutrient gap.

Shop on Thorne

Thorne

Zinc Picolinate

GLP-1 therapy commonly disrupts taste and smell. Zinc supports sensory recovery and immune function.

Shop on Thorne

Thorne

Vitamin B12 (Methylcobalamin)

B12 depletion is common on GLP-1 therapy and contributes to the fatigue members often report in weeks 2-4.

Shop on Thorne

Thorne

Vitamin D3 with K2

Rapid weight loss on GLP-1 increases bone density risk. D3 and K2 work together to support calcium utilization and bone health.

Shop on Thorne

Ritual

Essential for Women 18+

Women-specific multivitamin with forms of iron and folate that address the nutritional gaps women on GLP-1 most commonly face.

Shop on Ritual

Thorne

Iron Bisglycinate

Women reducing red meat intake on GLP-1 often become iron-deficient. This is the gentlest, most absorbable form.

Shop on Thorne

Thorne

Omega-3 with CoQ10

Cardiovascular support that stacks with the cardiac benefits of GLP-1 therapy itself. A long-term foundation supplement.

Shop on Thorne

Ritual

Essential Multivitamin

Clean-label, transparent-sourcing multi for ongoing micronutrient support once members are past the adjustment phase.

Shop on Ritual

By goal

Women's health

Ritual

Essential Protein

Clean-label daily protein shake for members struggling to hit protein targets when appetite is dramatically reduced.

Shop on Ritual

Ritual

Essential for Women 18+

Women-specific multivitamin with forms of iron and folate that address the nutritional gaps women on GLP-1 most commonly face.

Shop on Ritual

Thorne

Iron Bisglycinate

Women reducing red meat intake on GLP-1 often become iron-deficient. This is the gentlest, most absorbable form.

Shop on Thorne

Ritual

Essential Multivitamin

Clean-label, transparent-sourcing multi for ongoing micronutrient support once members are past the adjustment phase.

Shop on Ritual

By goal

GI & side effect support

Thorne

Magnesium Bisglycinate

Highly bioavailable form that supports GI motility and helps manage the nausea and digestive disruption common in the first month on GLP-1 therapy.

Shop on Thorne

Momentous

Collagen Peptides

Supports gut lining integrity during the early weeks when appetite is suppressed and food intake is limited.

Shop on Momentous

Affiliate disclosure

Vitalé Health participates in affiliate programs with supplement brands we trust and recommend. If you purchase through our links, we may earn a commission at no additional cost to you. All recommendations are based on clinical evidence and alignment with GLP-1 users' specific nutritional needs. Vitalé does not manufacture these products.

Results may vary. These products are not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.